melanocortin receptor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8485	THIQ		Melanocortin Receptor
	THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively).		Melanocortin Receptor
TP1898	HS024	HS 024	Melanocortin Receptor
	HS024 is a highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-...		Melanocortin Receptor
T7589	Afamelanotide acetate	afamelanotide	Melanocortin Receptor
	Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Protoporphyria.		Melanocortin Receptor
TP1889	MCL0020	MCL 0020	Melanocortin Receptor
	MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). Significantly reverses stress-induced anorexia but has no e...		Melanocortin Receptor
T5464	JNJ-10229570	JNJ10229570,UNII-N9IX402L35,JNJ 10229570	Melanocortin Receptor
	JNJ-10229570 (UNII-N9IX402L35) is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids.		Melanocortin Receptor
T7608	Bremelanotide Acetate	bremelanotide,PT-141 Acetate	Melanocortin Receptor
	Bremelanotide Acetate (PT-141 Acetate) is an agonist of melanocortin receptor (MCR) .		Melanocortin Receptor
TP1097	Melanotan I	[Nle4,D-Phe7]-α-MSH,Afamelanotide,MT-I	Others
	Melanotan I is a non-specific melanocortin receptor (MCR) agonist, an α-melanocyte-stimulating hormone (α-MSH) analog, which is injected subcutaneously to increase the amount of melanin in the skin Melanotan I is used as...		Others
T7813	α-MSH	MSH, amide,CZEN-002,α-Melanocyte-Stimulating Hormone (MSH), amide	Melanocortin Receptor , Adenylyl cyclase
	α-MSH (MSH, amide) is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.		Melanocortin Receptor , Adenylyl cyclase
T7769	Nonapeptide-1	Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-,Melanostatine™ 5	Others
	Nonapeptide-1 (Melanostatine™ 5) can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions.		Others
T7627	Adrenocorticotropic Hormone (ACTH) (4-10), human	Adrenocorticotropic Hormone (ACTH) (4-10),ACTH (4-10), human,Acth (4-10)	Melanocortin Receptor
	Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .		Melanocortin Receptor
T8231	Adrenocorticotropic Hormone (ACTH) (1-39), human	ACTH (1-39), human	Others
	Adrenocorticotropic Hormone (ACTH) (1-39), human (ACTH (1-39), human) is an agonist of melanocortin receptor.		Others
T7627L	Adrenocorticotropic Hormone (ACTH) (4-10) TFA	Adrenocorticotropic Hormone (ACTH) (4-10) TFA(4037-01-8(free base)),Acth (4-10)	Melanocortin Receptor
	Adrenocorticotropic Hormone (ACTH) (4-10) TFA (Acth (4-10)) is an agonist of potent melanocortin(MC4R) receptor .		Melanocortin Receptor
TP1011L	ACTH (1-17) acetate		Melanocortin Receptor
	ACTH (1-17) acetate is a potent agonist at the human melanocortin 1 (MC1) receptor with high affinity(Ki = 0.21 nM).		Melanocortin Receptor
T69526	PF-07258669		Melanocortin Receptor
	PF-07258669 is a selective melanocortin 4 receptor (MC4) antagonist used in the study of cachexia and loss of appetite.		Melanocortin Receptor
TP1324	Melanotan (MT)-II		Melanocortin Receptor
	Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH).		Melanocortin Receptor
TP1004L	Beta-MSH (1-22) (human) acetate	Beta-MSH (1-22) (human) acetate (17908-57-5 Free base)	Melanocortin Receptor
	Beta-MSH (1-22) (human) acetate (Beta-MSH (1-22) (human) acetate (17908-57-5 Free base)) , is an endogenous melanocortin-4 receptor (MC4-R) agonist.		Melanocortin Receptor
T12882L	Setmelanotide Acetate(920014-72-8 free base)	RM-493 Acetate,IRC-022493 Acetate,BIM-22493 Acetate	Melanocortin Receptor
	Setmelanotide Acetate(920014-72-8 free base) (RM-493 Acetate) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).		Melanocortin Receptor
TP1893L1	[D-Trp8]-γ-MSH acetate(321351-81-9 free base)		Melanocortin Receptor
	Selective melanocortin 3 (MC3) receptor agonist (IC50 values are 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors respectively). Displays anti-inflammatory efficacy.		Melanocortin Receptor
TP2212L	A-MSH, amide Acetate(581-05-5 free base)		Melanocortin Receptor
	a-MSH, amide Acetate as an endogenous neuropeptide. It is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelano...		Melanocortin Receptor
TP1952L	PG 106 acetate	PG 106 acetate(944111-22-2 Free base)	Melanocortin Receptor
	PG 106 acetate is an effective and selective antagonist of the human melanocortin 3 (hMC3) receptor with an IC50 of 210 nM. PG 106 acetate has no activity with the hMC5 receptor and hMC4 receptors with an EC50 of 9900 nM...		Melanocortin Receptor